Takahito Yagi Selected Research

Transcription Factor 3

5/2016	Loss of Runt-related transcription factor 3 induces resistance to 5-fluorouracil and cisplatin in hepatocellular carcinoma.
8/2013	Loss of runt-related transcription factor 3 induces gemcitabine resistance in pancreatic cancer.
12/2012	Runt-related transcription factor 3 reverses epithelial-mesenchymal transition in hepatocellular carcinoma.
9/2011	Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.
1/2011	Loss of runt-related transcription factor 3 expression leads hepatocellular carcinoma cells to escape apoptosis.

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Takahito Yagi Research Topics

Disease

31	Hepatocellular Carcinoma (Hepatoma) 06/2022 - 11/2002
27	Neoplasms (Cancer) 06/2022 - 01/2005
13	Neoplasm Metastasis (Metastasis) 03/2022 - 07/2006
8	Pancreatic Neoplasms (Pancreatic Cancer) 09/2022 - 05/2011
7	Hepatitis B 02/2019 - 01/2007
7	Hepatitis 10/2018 - 07/2008
6	Carcinoma (Carcinomatosis) 03/2022 - 01/2006
6	Liver Failure 03/2022 - 11/2007
6	Hemorrhage 04/2021 - 11/2007
6	Infections 02/2019 - 04/2006
6	Acute Liver Failure (Fulminant Hepatic Failure) 02/2019 - 04/2002
6	Liver Cirrhosis (Hepatic Cirrhosis) 02/2019 - 01/2007
5	Hepatitis C 04/2021 - 04/2009
5	Pathologic Constriction (Stenosis) 01/2015 - 09/2009
4	Cholangiocarcinoma 02/2022 - 07/2016
4	Lymphatic Metastasis 01/2022 - 01/2012
4	Reperfusion Injury 01/2016 - 10/2003
3	Adenocarcinoma 09/2022 - 09/2021
3	Neuroendocrine Tumors (Neuroendocrine Tumor) 05/2022 - 03/2020
3	Pulmonary Hypertension 03/2020 - 05/2018
3	Massive Hepatic Necrosis 10/2018 - 01/2007
3	Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis) 12/2014 - 04/2011
3	Hepatic Encephalopathy 04/2014 - 10/2012
3	Body Weight (Weight, Body) 08/2013 - 05/2006
2	Pain (Aches) 01/2022 - 12/2012
2	Neoplasms, Cystic, Mucinous, and Serous 01/2022 - 01/2015
2	End Stage Liver Disease 02/2019 - 01/2009
2	Insulin Resistance 12/2018 - 04/2013
2	Sarcopenia 05/2017 - 10/2016
2	Biliary Atresia 02/2017 - 04/2011
2	Portal Hypertension 12/2016 - 09/2008
2	Stomach Neoplasms (Stomach Cancer) 05/2016 - 01/2011
2	Aneurysm (Aneurysms) 01/2015 - 01/2005
2	Fibrosis (Cirrhosis) 01/2015 - 04/2011
2	Necrosis 04/2014 - 10/2004
2	Hepatoblastoma 03/2014 - 08/2011
2	Colorectal Neoplasms (Colorectal Cancer) 02/2013 - 01/2006
2	Ischemia 02/2012 - 01/2008
2	Diabetes Complications 09/2010 - 03/2010
2	Wounds and Injuries (Trauma) 01/2008 - 12/2004
2	Inflammation (Inflammations) 01/2008 - 09/2002
1	Primitive Neuroectodermal Tumors (PNET) 05/2022
1	Gallstones (Gallstone) 03/2022
1	Pancreatitis 03/2022
1	Congenital Diaphragmatic Hernias 01/2022
1	Fever (Fevers) 01/2022
1	Dyspnea (Shortness of Breath) 01/2022
1	Esophageal Neoplasms (Esophageal Cancer) 12/2021
1	Mucinous Cystadenocarcinoma 09/2021
1	acquired Factor 8 deficiency 04/2021
1	Hemophilia A (Haemophilia) 04/2021

Drug/Important Bio-Agent (IBA)

7	Immunoglobulins (Immunoglobulin)IBA 02/2019 - 01/2007
7	Proteins (Proteins, Gene)FDA Link 07/2016 - 05/2011
6	hepatitis B hyperimmune globulinIBA 02/2019 - 01/2007
5	Transcription Factor 3IBA 05/2016 - 01/2011
4	AntigensIBA 01/2021 - 12/2011
3	Cisplatin (Platino)FDA LinkGeneric 01/2017 - 11/2015
3	DNA (Deoxyribonucleic Acid)IBA 07/2016 - 05/2006
3	InterferonsIBA 06/2014 - 01/2014
3	RNA (Ribonucleic Acid)IBA 06/2014 - 04/2009
3	Heme (Haem)IBA 02/2012 - 12/2004
3	CytokinesIBA 07/2008 - 10/2004
3	Interleukin-6 (Interleukin 6)IBA 07/2008 - 10/2004
2	B7-H1 AntigenIBA 01/2022 - 11/2019
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 02/2013
2	AntibodiesIBA 01/2022 - 11/2019
2	Pharmaceutical PreparationsIBA 08/2020 - 07/2015
2	VaccinesIBA 02/2019 - 07/2015
2	HLA Antigens (Human Leukocyte Antigens)IBA 03/2017 - 04/2013
2	Tacrolimus (Prograf)FDA LinkGeneric 02/2017 - 04/2011
2	Monoclonal AntibodiesIBA 01/2016 - 04/2009
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 07/2015 - 04/2006
2	Calcineurin InhibitorsIBA 07/2015 - 08/2013
2	Alanine Transaminase (SGPT)IBA 06/2014 - 10/2004
2	Immunosuppressive Agents (Immunosuppressants)IBA 04/2011 - 01/2009
2	Advanced Glycation End ProductsIBA 09/2010 - 03/2010
2	Interleukin-18 (Interleukin 18)IBA 04/2006 - 09/2002
1	Indocyanine Green (Cardio-Green)FDA LinkGeneric 06/2022
1	C-Reactive ProteinIBA 01/2022
1	Carboplatin (JM8)FDA LinkGeneric 09/2021
1	Paclitaxel (Taxol)FDA LinkGeneric 09/2021
1	Factor VIIa (Activated Factor VII)IBA 04/2021
1	Factor VIII (Coagulation Factor VIII)IBA 04/2021

Therapy/Procedure

48	Liver Transplantation 03/2020 - 04/2002
22	Hepatectomy 03/2022 - 01/2006
12	Therapeutics 09/2022 - 04/2002
10	Pancreaticoduodenectomy 03/2022 - 01/2005
9	Transplantation 03/2020 - 04/2006
8	Drug Therapy (Chemotherapy) 12/2021 - 08/2011
5	Pancreatectomy 09/2022 - 01/2015
4	Lymph Node Excision (Lymph Node Dissection) 05/2022 - 12/2013
4	Radiofrequency Ablation 01/2020 - 11/2002
4	Ligation 09/2010 - 01/2005
2	Operative Surgical Procedures 03/2022 - 03/2012
2	Segmental Mastectomy (Lumpectomy) 04/2021 - 03/2008
2	Stents 01/2015 - 09/2009
2	Laparotomy 02/2011 - 01/2005
1	Endoscopic Sphincterotomy 03/2022
1	Renal Dialysis (Hemodialysis) 01/2022
1	Esophagectomy 12/2021